Camille De Pazzis made an entry into American television in 2012 with the military drama series, Last Resort, portraying the role of Sophie Girard. She was one of the main cast in the short-lived series, which ended in January 2013.
Two years later, she was seen in the Kevin Bacon starrer psychological thriller, The Following, as the recurring character Gisele. In late 2014, it was announced that the actress would be appearing as a series regular in the third installment of Netflix original horror series, Hemlock Grave. She portrayed the mysterious Annie Archambeau in the series. Camille's latest role in the American television was in an episode of the superhero action series, Agents of S.H.I.E.L.D.
Before her foray into American television, Camille had bagged roles in more than a few French series. In 2000, Camille appeared in an episode of the French crime series, Nestor Burma. With a starring role as Ines in hit teenage series, La vie devant nous, in 2002, her popularity became wider.
Since then, she has appeared in various other French television series such as Les enquêtes d'Éloïse Rome, Quai n° 1, Alex Santana négociateur, La vies est à nous, Pigalle la Nuit, and Nicolas Le Floch.